Chaga
Antioxidant Support | Natural Immunity | Aging well
Wild-harvested Chaga. Triple-extracted. Liquid form. Formulated for those seeking to integrate what is often considered the most antioxidant-rich superfood in the world. Traditionally used for its richness in natural compounds associated with immune balance, cellular support and adaptogenic properties.
EU-Certified Organic | Made in France | Lab-Tested
Extracted on Wild Mushrooms | No Fillers | 100% Natural Formulation
- Regular price
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€104,00 - Regular price
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€118,50 - Sale price
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€104,00
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1. For You ?
Embraced by those who move fast, recover slow, and seek natural ways to restore balance.
Whether managing daily oxidative stress, recovering from intense activity, or looking to support your body natural defense systems over time, Chaga is for you if you care about longevity and want to integrate antioxidant-rich compounds into your routine to support recovery and long-term vitality.
2. Composition
Wild-harvested Organic Chaga - Inonotus obliquus - (Liquid Extract)
- 100% Wild-Grown from Forests - Certified Organic by Ecocert (EU Agriculture)
- Fruiting Body (100%)
- Mushroom Origin: Estonia (EE) - Some batches might contain wild harvested mushrooms from Ural Mountains (RU).
Other Ingredients: Purified Water, Organic Ethanol (20-24%)**
*Over 160 naturally occurring bioactive compounds have been documented in Chaga, including:
- Vitamins : B1, B2, B3, B5, D, K
- Betulin and Betulinic Acid
- Polysaccharides (Beta-glucans)
- Triterpenoids (inotodiol, lanosterol)
- Melanin
- Antioxidants (Superoxide Dismutase - SOD, Phenolic compounds)
- Phytosterols (ergosterol)
* Source: PubChem - Inonotus obliquus
Natural - Products
**Note: Ethanol is used as a solvent to extract and stabilize bioactive compounds and enhance product bioavailability.
3. Independent Studies
1. Research on Chaga’s Effects on Oxidative Stress in Cells & DNA protection : A study investigated the effects of Chaga extract on oxidative DNA damage in human lymphocytes. Researchers found that Chaga showed over 40% reduction in DNA fragmentation caused by hydrogen peroxide exposure (H2O2). These results suggest that compounds in Chaga may help protect cellular DNA from oxidative stress. Link to Study : BioFactors. 2004
2. Research on Anti-Inflammatory Effects of Chaga Extracts: A study investigated the anti-inflammatory properties of Chaga extracts on LPS-stimulated RAW 264.7 macrophage cells. The results indicated that various Chaga extracts significantly reduced the production of nitric oxide and pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-1β, suggesting potential anti-inflammatory activity. Link to Study : Molecules. 2022.
3. In Vitro Research on Chaga and Lung Cell Line Activity: A 2019 in vitro study investigated the effects of hot water extracts of Inonotus obliquus (Chaga mushroom) on a human lung adenocarcinoma cell line (A549) after 72 hours of incubation. The research observed a reduction in cell proliferation under lab conditions. Link to Study : Mircrobiology. 2019.
4. In Vivo Study on Chaga Polysaccharides and Glucose Metabolism : A 2017 in vivo study explored the effects of Inonotus obliquus polysaccharides (IOPS) in mice with diet- and streptozotocin-induced type 2 diabetes. Researchers observed improvements in markers related to glucose metabolism, insulin sensitivity, and antioxidant activity in liver tissue. The study also examined molecular pathways such as PI3K-Akt and GLUT4 translocation, contributing to research on Chaga’s potential role in metabolic regulation. Link to Study : Biomed Pharmacother. 2017.
5. In Vitro Study on Chaga and Human Liver Cell Lines : A 2008 in vitro study investigated the effects of hot water extracts from Inonotus obliquus (Chaga mushroom) on two human liver cell lines (HepG2 and Hep3B). Researchers observed reduced cell proliferation and changes in cell cycle markers under laboratory conditions. These findings contribute to ongoing research on the cellular activity of Chaga-derived compounds. Link to Study : World J Gastroenterol. 2008.
For more insights, Click here or visit the Scientific Resources section below on this page.
These studies are exploratory and do not constitute health claims. They are displayed here for educational purposes only. Chaga is not intended to diagnose, treat, or prevent any disease.
4. Transparency & Lab Analysis
From raw mushroom to final drop, we oversee every step in our own lab. No outsourcing, no shortcuts. Each batch is lab-tested for purity and screened for pesticides, heavy metals, and microbial residues.
We use only glass and stainless steel to eliminate the risk of microplastic contamination.
We’re one of the few producers in this industry to go this far, controlling every detail from extraction to bottling to ensure unmatched quality and safety.
Chaga's Most Studied Natural Compounds
Melanins
Triterpenoids
Betulinic Acid
Our interest in extracting Chaga began by deep-diving into 30+ publications*.
What is Chaga ?
Chaga (Inonotus obliquus) is a slow-growing functional mushroom that grows primarily on birch trees in cold, forested regions. Traditionally used across Siberia and Northern Europe, it is known for its dense concentration of naturally occurring compounds.
Often called the “King of Mushrooms,” Chaga is known for its dense concentration of naturally occurring compounds.
It stands out for its remarkably high antioxidant potential, with some lab analyses reporting ORAC values above 140,000 μmol TE/100g, among the highest recorded. While ORAC is no longer an official USDA benchmark, Chaga’s profile, rich in betulinic acid, melanin, polyphenols, and β-glucans, continues to be explored in preclinical research for their potential roles in antioxidant activity, immune modulation, and cellular protection.*
Explore our TriExtract formula, combining three organic mushroom extracts : Lion’s Mane, Reishi, and Chaga for all-in-one daily support.
For Whome ?
Our Chaga extract is formulated for :
Longevity-minded adults
Integrating superfood-based nutrition into their routine to help manage oxidative stress as part of a natural, wellness-focused aging routine.
Individuals under high stress or seeking natural support for recovery
For those navigating physically or mentally exhausting periods and looking for plant-based alternatives to support recovery and restore daily balance.
Why ?
Over one out of three (35%) British adults report fatigue as the main barriers to changing their diet and increasing physical activity Nearly half 49% of 24-35 year-olds mention fatigue as a significant factor.*
But fatigue isn’t just about low energy. It’s about recovery, resilience, and how well the body adapts to stress over time.
This rising need for natural, long-term support is fueling interest in functional ingredients like Chaga. Not a stimulant. Not a quick fix. But a fungi-based ally for those looking to restore balance and build a more resilient foundation, day after day.
*Scientific Ressources
- MSKCC Integrative Medicine database - Chaga Mushroom
- Youn MJ, Kim JK, Park SY, et al. Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells. World J Gastroenterol. Jan 28 2008;14(4):511-517.
- Hyun KW, Jeong SC, Lee DH, Park JS, Lee JS. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides. Jun 2006;27(6):1173-1178.
- Park YM, Won JH, Kim YH, et al. In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus. J Ethnopharmacol. Oct 3 2005;101(1-3):120-128.
- Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol. Jun 19 2008;118(1):7-13.
- Lee SH, Hwang HS, Yun JW. Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT-29 human colon cancer cells. Phytother Res. Apr 15 2009.
- Zhong XH, Ren K, Lu SJ, Yang SY, Sun DZ. Progress of research on Inonotus obliquus. Chin J Integr Med. Apr 2009;15(2):156-160.
- Youn MJ, Kim JK, Park SY, et al. Potential anticancer properties of the water extract of Inonotus [corrected] obliquus by induction of apoptosis in melanoma B16-F10 cells. J Ethnopharmacol. Jan 21 2009;121(2):221-228.
- Najafzadeh M, Reynolds PD, Baumgartner A, Jerwood D, Anderson D. Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease. Biofactors. 2007;31(3-4):191-200.
- Ham SS, Kim SH, Moon SY, et al. Antimutagenic effects of subfractions of Chaga mushroom (Inonotus obliquus) extract. Mutat Res. Jan 10 2009;672(1):55-59.
- Caifa Chen WZ, Gao X, Xiang X, et al. Aqueous Extract of Inonotus obliquus (Fr.) Pilat (Hymenochaetaceae) Significantly Inhibits the Growth of Sarcoma 180 by Inducing Apoptosis. Am J Pharmacol Toxicol. 2007. 2(1):10-17.
- Shashkina MY, Shashkin PN, Sergeev AV. Chemical and Medicobiological Properties of Chaga (Review). Pharmaceutical Chemistry Journal 2006. 40(10):560-568.
- Glamoclija J, Ciric A, Nikolic M, et al. Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal “mushroom”. J Ethnopharmacol. Mar 13 2015;162:323-332.
- Ning X, Luo Q, Li C, et al. Inhibitory effects of a polysaccharide extract from the Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), on the proliferation of human neurogliocytoma cells. Int J Med Mushrooms. 2014;16(1):29-36.
- Pan HH, Yu XT, Li T, et al. Aqueous extract from a Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), prevents herpes simplex virus entry through inhibition of viral-induced membrane fusion. Int J Med Mushrooms. 2013;15(1):29-38.
- Ying YM, Zhang LY, Zhang X, et al. Terpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquus. Phytochemistry. Dec 2014;108:171-176.
- Ko SK, Jin M, Pyo MY. Inonotus obliquus extracts suppress antigen-specific IgE production through the modulation of Th1/Th2 cytokines in ovalbumin-sensitized mice. J Ethnopharmacol. Oct 11 2011;137(3):1077-1082.
- Yoon TJ, Lee SJ, Kim EY, et al. Inhibitory effect of chaga mushroom extract on compound 48/80-induced anaphylactic shock and IgE production in mice. Int Immunopharmacol. Apr 2013;15(4):666-670.
- Giridharan VV, Thandavarayan RA, Konishi T. Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus - a medicinal mushroom. Food Funct. Jun 2011;2(6):320-327.
- Mishra SK, Kang JH, Kim DK, et al. Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice. J Ethnopharmacol. Sep 28 2012;143(2):524-532.
- Yue Z, Xiuhong Z, Shuyan Y, et al. Effect of Inonotus Obliquus Polysaccharides on physical fatigue in mice. J Tradit Chin Med. Aug 2015;35(4):468-472.
- Kang JH, Jang JE, Mishra SK, et al. Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the beta-catenin pathway in colorectal cancer. J Ethnopharmacol. Sep 15 2015;173:303-312.
- Lee HS, Kim EJ, Kim SH. Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells. Nutr Res Pract. Apr 2015;9(2):111-116.
- Zhao LW, Zhong XH, Yang SY, et al. Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells. Asian Pac J Cancer Prev. 2014;15(7):3195-3199.
- Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol. Jun 2014;81(6):440-444.
- Sun Y, Yin T, Chen XH, et al. In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilat (Aphyllophoromycetideae). Int J Med Mushrooms. 2011;13(2):121-130.
- Wang Q, Mu H, Zhang L, et al. Characterization of two water-soluble lignin metabolites with antiproliferative activities from Inonotus obliquus. Int J Biol Macromol. Mar 2015;74:507-514.
- Wang J, Hu W, Li L, et al. Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes. PLoS One. 2017;12(6):e0180476. doi: 10.1371/journal.pone.0180476
- Baek J, Roh HS, Baek KH, et al. Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells. J Ethnopharmacol. Oct 5 2018;224:63-75.
- Lee S, Lee HY, Park Y, et al. Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature. J Korean Med Sci. 2020 May 18;35(19):e122.
- Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore). 2022 Mar 11;101(10):e28997.
Most Chaga Supplements Stop at Standard. We Don’t.
Every detail, from sourcing to formulationn is considered to ensure that when you choose Polyextract, you’re choosing an extract that goes far beyond industry standards.
No shortcuts. No compromises. Just premium quality, start to finish.
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Vegan
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Gluten-Free
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Certified Organic
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No Animal Testing
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No-Binders
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Allergen-Free
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100% EU Ingredients
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GMO-Free
Making each dose work harder for you.
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Selection
The concentration of active compounds in mushrooms depends heavily on how the fungi is grown.
That’s why we’ve established a direct partnership with our organic mushroom farmer in Belgium allowing us to oversee everything from the strain selection and substrate composition to the harvest timing and delivery conditions.
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Innovation
We spent 2 years developing our extraction protocol, conducting more than 50 formulation trials and analyzing each batch in depth.
Using high-end analytical tools like HPLC, we optimized our method to extract the broadest spectrum of compounds. This work laid the foundation for an ongoing scientific thesis, positioning Polyextract at the forefront of research in the field.
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Extraction
To capture all active compounds, we apply up to 5 extraction techniques per mushroom, tailored by species and compound profile.
Each method is optimized individually, then recombined to ensure molecular stability and bioavailability. This multi-step approach makes our extraction process unique in the industry, built not on assumption, but on data.
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Assimilation
Our extracts allow faster, more efficient absorption. This is thanks to our liquid formulation, which bypasses the digestive breakdown required by capsules or powders.
Think of it as a pre-digested supplement. When active compounds are pre-dissolved, your body works less and absorbs more. Some compounds have shown up to 185× better absorption in liquid form.
Questions ? We're here to help you.
How do I take Chaga Extract ?
Take x1 full dropper pipette (1 mL) per day.
Mix it into a glass of water or any other cold liquid.You can also take it directly under the tongue.
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For best results:
- Take consistently. Chaga works best when used daily over time.
- Avoid mixing with hot liquids, as heat may affect the stability of some sensitive compounds.
- Take at the same time each day, ideally within one hour of your usual wake-up and wind-down times to stay aligned with your circadian rhythm.
- During high-demand periods (mental or physical), you may temporarily increase to 30–40 drops per day (1.5 to 2 full pipettes), split between morning and evening.
- Start with 5 drops in the morning and 5 in the evening. Then, Increase daily by +2 drops total (add 1 drop to each dose) until you reach 20 drops per day by day 6 (10 in the morning, 10 in the evening).
- Always Shake well before use.
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x1 dropper pipette = 1 mL = 0.0338 oz. ≈ x20 dropps
Do not exceed 50 drops per day.
Do not use if under 18 years old, or if you are a pregnant/breastfeeding women.
Stop use if adverse reactions develop.
What’s Inside the Chaga Extract ?
Wild Harvested Organic Chaga - Inonotus Obliquus - (Liquid Extract)
- 100% Wild-Grown from Forests - Certified Organic by Ecocert (EU Agriculture)
- Fruiting Body (100%)
- Mushroom Origin: Estonia (EE) - Some batches might contain wild harvested mushrooms from Ural Mountains (RU).
Other Ingredients: Purified Water, Food Grade Organic Ethanol (20-24%)*
And nothing else !
*Note: Ethanol is used as a solvent to extract and stabilize bioactive compounds and enhance product bioavailability.
Why should I choose Polyextract Supplement ?
Chaga is traditionally used by individuals seeking support during periods of stress, fatigue, or recovery. It's often incorporated into daily routines by those who value natural, antioxidant-rich compounds backed by a growing body of scientific interest.
Taking Chaga in a liquid, bioavailable form, like the one we offer at Polyextract, allows access to its full spectrum of naturally occurring compounds, without needing to brew or prepare it from raw chunks.
Our triple-extraction process captures and preserves key actives such as betulinic acid, melanin, and polysaccharides, delivering them in a form the body can absorb more efficiently.
Compared to raw mushroom or standard powders, our extract offers superior bioavailability and fits effortlessly into your daily rhythm.
When will I feel something?
Everyone responds differently. Some users report feeling more balanced or resilient within 2 to 4 weeks of consistent use, but Chaga isn’t about instant effects. Like many functional compounds, its value builds over time.
The changes may be subtle at first, such as smoother recovery, steadier energy, or feeling less run down, but they often reflect deeper, long-term support at the cellular level.
Even if you don’t “feel” something right away, the bioactive compounds are working in the background, supporting your body’s natural rhythms and processes in ways that accumulate quietly, day by day.
What does Chaga Mushroom extract do?
Polyextract’s Chaga extract contains a broad spectrum of naturally occurring compounds, including betulinic acid, melanin, polyphenols, and polysaccharides, extracted from wild-harvested, organic fruiting bodies.
These compounds are being studied for their potential roles in areas such as antioxidant activity, cellular protection, immune modulation, and stress-related recovery.
You can explore the research associated with these compounds in our Scientific Reference Library.
Can I take Chaga extract with other supplements or medications?
Yes, many people include Chaga in their broader supplement routine and there aren’t any reports of side effects from using chaga mushroom.
However, our herbal and fungal extracts are much more concentrated than the ingredients you’d use in cooking. If you're combining them with other products, we recommend spacing out doses and observing how your body responds.
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As with any supplement, it's best to consult your healthcare provider before starting, especially if you're taking prescription medication or managing a health condition. This is particularly important if you’re using hypoglycemic agents, as in vitro studies suggest Chaga may have additive effects on lowering blood sugar. Similarly, Chaga has shown antiplatelet activity in animal models, which may potentially interact with anticoagulant or antiplatelet medications. Although clinical significance is not yet established, it’s best to remain cautious.
Who It’s For ?
Chaga is especially relevant for adults 30+ looking to manage daily stress and age well with the addition of antioxidant-rich compounds to their nutrition.
From 30 to 80 years old, Chaga fits into the routines of those who want to feel more balanced, restore energy, and build a resilient foundation over time.
Ideal for adults of all ages facing facing demanding conditions and looking to support wellness and recovery naturally and consistently.
