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TriExtract : Chaga, Reishi, Lion's Mane

Cognitive support | Immune balance | Cellular function

Our most complete formula. Triple-extracted blend of Chaga, Reishi and Lion's Mane in liquid form.

Formulated for those seeking the combined benefits of nature’s most studied compounds, traditionally associated with mental clarity, immune defense, and adaptive balance.

EU-Certified Organic | Made in France | Lab-Tested

Extracted on Fresh Mushrooms | No Fillers | 100% Natural Formulation

Regular price
€134,00
Regular price
€153,00
Sale price
€134,00
Tax included. Shipping calculated at checkout.
QUANTITY
1. For You ?

For performance-focused individuals, who want to think clearly, feel balanced, and stay strong.

From high-stress professionals to health-conscious adults 40+, TriExtract fits routines focused on staying sharp, maintaining immune readiness, and supporting long-term wellness.

One formula. Three mushrooms. All-in-one full-spectrum support.

2. Composition

1/3 Wild-Harvested Organic Chaga - Inonotus obliquus

1/3 Organic Reishi Ganoderma lucidum

1/3 Organic Lion's Mane Hericium erinaceus

  • 3x Extracted Liquid Formulation
  • 100% Organic - Certified by Ecocert (EU Agriculture)
  • Fruiting Body (100%) - no fillers
  • Origin: Belgium (Reishi, Lion’s Mane), Estonia (Chaga) - Wild-harvested Chaga from the Ural Mountains may be used in some batches.

Other Ingredients: Purified Water, Organic food grade Alcohol (20-24%)**

*Cumultaed, Over 1,500 naturally occurring bioactive compounds have been documented in Chaga, Reishi, Lion's Mane, including:

  • Vitamins : B1, B2, B3, B5, D, K
  • Hericenones (Benzaldehydes)
  • Erinacines (Diterpenoids)
  • β-glucan (Polysaccharides)
  • Sterols
  • Peptides
  • Sterols
  • Antioxidants (Hericene)
  • Betulin and Betulinic Acid
  • ...

*Source: PubChem - Hericium erinaceus - Natural - Products | PubChem - Inonotus obliquus - Natural - Products | PubChem - Ganoderma lucidum Natural - Products

**Note: Ethanol is used as a solvent to extract and stabilize bioactive compounds and enhance product bioavailability.

3. Independent Studies

Lion's Mane

  • Long-Term Study on Cognitive Function in Aging: A 2020 placebo-controlled study evaluated the use of Lion’s Mane extract over 49 weeks in adults experiencing age-related cognitive decline. Researchers recorded differences in test scores between groups, positioning Lion’s Mane as a compound of interest in cognitive aging research. Link to Study : Front Aging Neurosci. 2020

  • Lion’s Mane and Task Performance in Healthy Adults : A double-blind, placebo-controlled pilot study explored the effects of Lion’s Mane supplementation over 28 days in healthy adults aged 18–45. Researchers observed differences in task response speed shortly after intake, as well as a trend toward reduced self-reported stress after sustained use. Link to Study : Nutrients. 2023

  • Neurotrophic properties & exploration of Nerve Growth Factor (NGF) Stimulation : Research has investigated how compounds in Lion’s Mane, particularly hericenones and erinacines, may stimulate nerve growth factor (NGF) synthesis in cells. Link to Study : Int J Med Mushrooms - 2013.

Reishi

  • Study on Immune Modulation in Healthy Adults : A placebo-controlled clinical trial evaluated the effects of Reishi derived beta-glucans in healthy individuals. Researchers noted measurable changes in immune markers, suggesting an immunomodulatory effect without reported adverse outcomes.
    Link to Study: Foods. 2023.

  • Preclinical Exploration of Sleep-Supportive Properties: An animal study assessed the impact of Reishi extracts on rest duration in rats. The results indicated an increase in sleep time, supporting traditional use in calming nighttime routines. Link to Study : Journal of Ethnopharmacology. 2012.

  • Laboratory Research on Anti-Inflammatory Properties of Reishi Compounds: Researchers isolated specific triterpenoids from Ganoderma lucidum (Reishi) and tested their effects on inflammation markers in vitro. Certain compounds showed the ability to inhibit pro-inflammatory pathways under controlled lab conditions. Link to Study : Food and Chemical Toxicology. 2021.

Chaga

  • Research on Chaga’s Effects on Oxidative Stress in Cells & DNA protection : A study investigated the effects of Chaga extract on oxidative DNA damage in human lymphocytes. Researchers found that Chaga showed over 40% reduction in DNA fragmentation caused by hydrogen peroxide exposure (H2O2). These results suggest that compounds in Chaga may help protect cellular DNA from oxidative stress. Link to Study : BioFactors. 2004

  • In Vitro Research on Chaga and Lung Cell Line Activity: A 2019 in vitro study investigated the effects of hot water extracts of Inonotus obliquus (Chaga mushroom) on a human lung adenocarcinoma cell line (A549) after 72 hours of incubation. The research observed a reduction in cell proliferation under lab conditions. Link to Study : Mircrobiology. 2019.

  • Research on Anti-Inflammatory Effects of Chaga Extracts: A study investigated the anti-inflammatory properties of Chaga extracts on LPS-stimulated RAW 264.7 macrophage cells. The results indicated that various Chaga extracts significantly reduced the production of nitric oxide and pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-1β, suggesting potential anti-inflammatory activity. Link to Study : Molecules. 2022.

Click here for more insights, on Chaga, Reishi or Lion's Mane or visit the Scientific Resources section below on this page.

These studies are exploratory and do not constitute health claims. They are displayed here for educational purposes only. Chaga, Reishi, Lion’s Mane is not intended to diagnose, treat, or prevent any disease.

4. Transparency & Lab Analysis

From raw mushroom to final drop, we oversee every step in our own lab. No outsourcing, no shortcuts. Each batch is lab-tested for purity and screened for pesticides, heavy metals, and microbial residues.

We use only glass and stainless steel to eliminate the risk of microplastic contamination. We’re one of the few producers in this industry to go this far, controlling every detail from extraction to bottling to ensure unmatched quality and safety.

TriExtract bottle with Chaga, Reishi, Lion&
TriExtract : Chaga, Reishi, Lion&
Triextract : des champignons fonctionnels tel que le Lion’s Mane, Chaga et Reishi, reconnus pour leurs bienfaits
Triextract dropper with golden liquid, showcasing the essence of Chaga, Reishi, and Lion&
Étiquette du produit Triextract, présentant les extraits concentrés de champignons Chaga, Reishi et Lion’s Mane par Polyextract.
Extrait concentré de champignons Triextract (Chaga, Reishi, Lion’s Mane) par Polyextract, conditionné dans un flacon compte-gouttes en verre ambré de 30ml
Extrait concentré de champignons Triextract (Chaga, Reishi, Lion’s Mane) par Polyextract, conditionné dans un flacon compte-gouttes en verre ambré de 60ml

The Polyextract Difference

  • 83%

    of daily users described a noticeable improvement in their general sense of well-being and mental focus after starting TriExtract.*

  • 96%

    of users said they would recommend Polyextract to a friend or family member.*

  • 15 Days

    On average, users report noticing a difference around 15 days after starting TriExtract.*

*Based on a survey of n=21 early testers evaluating self-perceived outcomes.

Chaga, Reishi, Lion's Mane Most Studied Natural Compounds

  • Erinacines

  • Hericenones

  • Ganoderic Acids

  • Ling Zhi-8

  • Betulinic Acid

  • Beta-Glucans

Our interest in formulating TriExtract began by deep-diving into 100+ publications*.

Why Chaga, Reishi, Lion's Mane ?

Because no single mushroom does it all.

Our triple-extract formula combines the complementary strengths of three of the most researched functional mushrooms—each chosen for its unique, evidence-supported properties:

  • Chaga
    Rich in natural antioxidants like melanin and polyphenols, Chaga is traditionally used to support immune resilience and cellular defense.

  • Reishi
    Often referred to as the “mushroom of longevity,” Reishi is valued for its adaptogenic properties and its role in promoting internal balance and immune modulation.

  • Lion's Mane
    Known for its neurotrophic compounds like hericenones and erinacines, Lion’s Mane is studied for its potential to support memory, focus, and cognitive health.

Together, they offer a well-rounded approach to daily vitality, helping support immune function, cognitive clarity, and oxidative stress protection.

Who is it for?

Adults 40+ seeking daily support for energy, clarity, and looking into nutrition to age well
Whether you're navigating the demands of a busy career, managing family responsibilities, or optimizing your aging routine, this formula is designed to support your baseline vitality.

Individuals looking to support cognitive function and immune balance
Individuals seeking to complement their routine with natural ingredients studied for their role in supporting brain function, immune modulation, and cellular protection as part of a proactive wellness routine.

Those interested in science-backed functional ingredients
If you're drawn to bioactive nutrition & superfood supplementation supported by both tradition and preclinical research, this formula is made for you.

What is Chaga ?

Chaga (Inonotus obliquus) is a slow-growing fungus that primarily thrives on birch trees in cold climates, such as Northern Europe and Siberia. Recognizable by its dark, charcoal-like exterior, it has been used in traditional wellness practices for centuries

Chaga mushroom is known for its high antioxidant potential, with one of the highest ORAC (Oxygen Radical Absorbance Capacity) values ever recorded in laboratory testing (sometimes reported above 140,000 μmol TE/100g). This reflects its strong ability to neutralize free radicals under lab conditions. While ORAC is no longer an official USDA metric since 2012, Chaga’s antioxidant profile, linked to polyphenols, melanin, and triterpenes continue to draw scientific interest and are currently studied for their potential roles in supporting the body's antioxidant defenses and maintaining cellular balance.

Learn more about our pure Chaga extract.

What is Lion's Mane ?

Lion’s Mane (Hericium erinaceus) is a white, cascading mushroom that resembles a lion’s mane, naturally growing on hardwood trees.

It has gained modern interest due to its content of hericenones, erinacines, and β-glucans. These compounds are being studied for their potential role in supporting nervous system health, neuroplasticity, and antioxidant activity in preclinical settings.

Lion’s Mane is traditionally used by those seeking focus, clarity, and long-term cognitive balance.

Learn more about our pure Lion's Mane extract.

What is Reishi

Reishi (Ganoderma lucidum) is a woody, shelf-like mushroom long revered in East Asian traditions, where it’s often called the “mushroom of immortality.”

Its bioactive profile includes polysaccharides, triterpenes (e.g., ganoderic acids), and phenolic compounds, which are being investigated in preclinical research for their potential to support immune regulation, help the body adapt to stress, and maintain physiological equilibrium.

Learn more about our pure Reishi extract.

*Scientific Ressources

  1. MSKCC - Integrative Medicine database - Lion's Mane
  2. MSKCC Integrative Medicine database - Chaga Mushroom
  3. MSKCC Integrative Medicine database - Reishi Mushroom
  4. Khan MA, Tania M, Liu R, Rahman MM. Hericium erinaceus: an edible mushroom with medicinal values. J Complement Integr Med. May 24 2013;10doi:10.1515/jcim-2013-0001
  5. Tsai-Teng T, Chin-Chu C, Li-Ya L, et al. Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer’s disease-related pathologies in APPswe/PS1dE9 transgenic mice. J Biomed Sci. Jun 27 2016;23(1):49. doi:10.1186/s12929-016-0266-z
  6. Mori K, Obara Y, Moriya T, Inatomi S, Nakahata N. Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Biomed Res. Feb 2011;32(1):67-72. doi:10.2220/biomedres.32.67
  7. Li Y, Zhang G, Ng TB, Wang H. A novel lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from dried fruiting bodies of the monkey head mushroom Hericium erinaceumJ Biomed Biotechnol. 2010;2010:716515. doi:10.1155/2010/716515
  8. Abdulla MA, Fard AA, Sabaratnam V, et al. Potential activity of aqueous extract of culinary-medicinal Lion’s Mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) in accelerating wound healing in rats. Int J Med Mushrooms. 2011;13(1):33-9. doi:10.1615/intjmedmushr.v13.i1.50
  9. Wang M, Konishi T, Gao Y, Xu D, Gao Q. Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes). Int J Med Mushrooms. 2015;17(11):1055-60. doi:10.1615/intjmedmushrooms.v17.i11.50
  10. Vigna L, Morelli F, Agnelli GM, et al. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? Evid Based Complement Alternat Med. 2019;2019:7861297. doi:10.1155/2019/7861297
  11. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. Mar 2009;23(3):367-72. doi:10.1002/ptr.2634
  12. Saitsu Y, Nishide A, Kikushima K, Shimizu K, Ohnuki K. Improvement of cognitive functions by oral intake of Hericium erinaceus. Biomed Res. 2019;40(4):125-131. doi:10.2220/biomedres.40.125
  13. Li IC, Chang HH, Lin CH, et al. Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study. Front Aging Neurosci. 2020;12:155. doi:10.3389/fnagi.2020.00155
  14. Nagano M, Shimizu K, Kondo R, et al. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. Aug 2010;31(4):231-7. doi:10.2220/biomedres.31.231
  15. Docherty S, Doughty FL, Smith EF. The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients. Nov 20 2023;15(22)doi:10.3390/nu15224842
  16. Grozier CD, Alves VA, Killen LG, Simpson JD, O’Neal EK, Waldman HS. Four Weeks of Hericium erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition. Int J Exerc Sci. 2022;15(2):1366-1380.
  17. Li W, Zhou W, Kim EJ, Shim SH, Kang HK, Kim YH. Isolation and identification of aromatic compounds in Lion’s Mane Mushroom and their anticancer activities. Food Chem. Mar 1 2015;170:336-42. doi:10.1016/j.foodchem.2014.08.078
  18. Wang M, Zhang Y, Xiao X, Xu D, Gao Y, Gao Q. A Polysaccharide Isolated from Mycelia of the Lion’s Mane Medicinal Mushroom Hericium erinaceus (Agaricomycetes) Induced Apoptosis in Precancerous Human Gastric Cells. Int J Med Mushrooms. 2017;19(12):1053-1060. doi:10.1615/IntJMedMushrooms.2017024975
  19. Kim SP, Nam SH, Friedman M. Hericium erinaceus (Lion’s Mane) mushroom extracts inhibit metastasis of cancer cells to the lung in CT-26 colon cancer-tansplanted mice. J Agric Food Chem. May 22 2013;61(20):4898-904. doi:10.1021/jf400916c
  20. Friedman M. Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. J Agric Food Chem. Aug 19 2015;63(32):7108-23. doi:10.1021/acs.jafc.5b02914
  21. Hu JH, Li IC, Lin TW, et al. Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Hericium erinaceus Mycelia. Molecules. Apr 24 2019;24(8)doi:10.3390/molecules24081624
  22. Zhang CC, Yin X, Cao CY, Wei J, Zhang Q, Gao JM. Chemical constituents from Hericium erinaceus and their ability to stimulate NGF-mediated neurite outgrowth on PC12 cells. Bioorg Med Chem Lett. Nov 15 2015;25(22):5078-82. doi:10.1016/j.bmcl.2015.10.016
  23. Trovato A, Siracusa R, Di Paola R, et al. Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer’s disease pathogenesis. Immun Ageing. 2016;13:23. doi:10.1186/s12979-016-0078-8
  24. Wang LY, Huang CS, Chen YH, Chen CC, Chen CC, Chuang CH. Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS. Molecules. Sep 12 2019;24(18)doi:10.3390/molecules24183317
  25. Martínez-Mármol R, Chai Y, Conroy JN, et al. Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory. J Neurochem. Jun 2023;165(6):791-808. doi:10.1111/jnc.15767
  26. Li IC, Lee LY, Tzeng TT, et al. Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines. Behav Neurol. 2018;2018:5802634. doi:10.1155/2018/5802634
  27. Xie XQ, Geng Y, Guan Q, et al. Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study. Nutrients. Mar 21 2021;13(3)doi:10.3390/nu13031008
  28. Youn MJ, Kim JK, Park SY, et al. Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells. World J Gastroenterol. Jan 28 2008;14(4):511-517.
  29. Hyun KW, Jeong SC, Lee DH, Park JS, Lee JS. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides. Jun 2006;27(6):1173-1178.
  30. Park YM, Won JH, Kim YH, et al. In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus. J Ethnopharmacol. Oct 3 2005;101(1-3):120-128.
  31. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol. Jun 19 2008;118(1):7-13.
  32. Lee SH, Hwang HS, Yun JW. Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT-29 human colon cancer cells. Phytother Res. Apr 15 2009.
  33. Zhong XH, Ren K, Lu SJ, Yang SY, Sun DZ. Progress of research on Inonotus obliquus. Chin J Integr Med. Apr 2009;15(2):156-160.
  34. Youn MJ, Kim JK, Park SY, et al. Potential anticancer properties of the water extract of Inonotus [corrected] obliquus by induction of apoptosis in melanoma B16-F10 cells. J Ethnopharmacol. Jan 21 2009;121(2):221-228.
  35. Najafzadeh M, Reynolds PD, Baumgartner A, Jerwood D, Anderson D. Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease. Biofactors. 2007;31(3-4):191-200.
  36. Ham SS, Kim SH, Moon SY, et al. Antimutagenic effects of subfractions of Chaga mushroom (Inonotus obliquus) extract. Mutat Res. Jan 10 2009;672(1):55-59.
  37. Caifa Chen WZ, Gao X, Xiang X, et al. Aqueous Extract of Inonotus obliquus (Fr.) Pilat (Hymenochaetaceae) Significantly Inhibits the Growth of Sarcoma 180 by Inducing Apoptosis. Am J Pharmacol Toxicol. 2007. 2(1):10-17.
  38. Shashkina MY, Shashkin PN, Sergeev AV. Chemical and Medicobiological Properties of Chaga (Review). Pharmaceutical Chemistry Journal 2006. 40(10):560-568.
  39. Glamoclija J, Ciric A, Nikolic M, et al. Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal “mushroom”. J Ethnopharmacol. Mar 13 2015;162:323-332.
  40. Ning X, Luo Q, Li C, et al. Inhibitory effects of a polysaccharide extract from the Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), on the proliferation of human neurogliocytoma cells. Int J Med Mushrooms. 2014;16(1):29-36.
  41. Pan HH, Yu XT, Li T, et al. Aqueous extract from a Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), prevents herpes simplex virus entry through inhibition of viral-induced membrane fusion. Int J Med Mushrooms. 2013;15(1):29-38.
  42. Ying YM, Zhang LY, Zhang X, et al. Terpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquus. Phytochemistry. Dec 2014;108:171-176.
  43. Ko SK, Jin M, Pyo MY. Inonotus obliquus extracts suppress antigen-specific IgE production through the modulation of Th1/Th2 cytokines in ovalbumin-sensitized mice. J Ethnopharmacol. Oct 11 2011;137(3):1077-1082.
  44. Yoon TJ, Lee SJ, Kim EY, et al. Inhibitory effect of chaga mushroom extract on compound 48/80-induced anaphylactic shock and IgE production in mice. Int Immunopharmacol. Apr 2013;15(4):666-670.
  45. Giridharan VV, Thandavarayan RA, Konishi T. Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus - a medicinal mushroom. Food Funct. Jun 2011;2(6):320-327.
  46. Mishra SK, Kang JH, Kim DK, et al. Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice. J Ethnopharmacol. Sep 28 2012;143(2):524-532.
  47. Yue Z, Xiuhong Z, Shuyan Y, et al. Effect of Inonotus Obliquus Polysaccharides on physical fatigue in mice. J Tradit Chin Med. Aug 2015;35(4):468-472.
  48. Kang JH, Jang JE, Mishra SK, et al. Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the beta-catenin pathway in colorectal cancer. J Ethnopharmacol. Sep 15 2015;173:303-312.
  49. Lee HS, Kim EJ, Kim SH. Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells. Nutr Res Pract. Apr 2015;9(2):111-116.
  50. Zhao LW, Zhong XH, Yang SY, et al. Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells. Asian Pac J Cancer Prev. 2014;15(7):3195-3199.
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  52. Sun Y, Yin T, Chen XH, et al. In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilat (Aphyllophoromycetideae). Int J Med Mushrooms. 2011;13(2):121-130.
  53. Wang Q, Mu H, Zhang L, et al. Characterization of two water-soluble lignin metabolites with antiproliferative activities from Inonotus obliquus. Int J Biol Macromol. Mar 2015;74:507-514.
  54. Wang J, Hu W, Li L, et al. Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes. PLoS One. 2017;12(6):e0180476. doi: 10.1371/journal.pone.0180476
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  61. Hsu MJ, Lee SS, Lin WW. Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathwayJ Leukoc Biol. Jul 2002;72(1):207-216.
  62. Wang SY, Hsu ML, Hsu HC, et al. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytesInt J Cancer. Mar 17 1997;70(6):699-705.
  63. Wachtel-Galor S, Szeto YT, Tomlinson B, et al. Ganoderma lucidum (’Lingzhi’); acute and short-term biomarker response to supplementationInt J Food Sci Nutr. Feb 2004;55(1):75-83.
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  65. Gao Y, Zhou S, Jiang W, et al. Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patientsImmunol Invest. Aug 2003;32(3):201-215.
  66. Shieh YH, Liu CF, Huang YK, et al. Evaluation of the hepatic and renal-protective effects of Ganoderma lucidum in mice. Am J Chin Med. 2001;29(3-4):501-7.
  67. Noguchi M, Kakuma T, Tomiyasu K, et al. Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptomsAsian J Androl. Sep 2008;10(5):777-785.
  68. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of Ganoderma lucidum on platelet aggregationJ Tongji Med Univ. 1990;10(4):240-243.
  69. Wang CZ, Basila D, Aung HH, et al. Effects of Ganoderma lucidum extract on chemotherapy-induced nausea and vomiting in a rat modelAm J Chin Med. 2005;33(5):807-815.
  70. Gill SK, Rieder MJ. Toxicity of a traditional Chinese medicine, Ganoderma lucidum, in children with cancer. Can J Clin Pharmacol. Summer 2008;15(2):e275-285.
  71. Wang X, Zhao X, Li D, et al. Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in ratsBiol Pharm Bull. Sep 2007;30(9):1702-1706.
  72. Chen NH, Liu JW, Zhong JJ. Ganoderic Acid me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expressionJ Pharmacol Sci. Oct 2008;108(2):212-216.
  73. Li YB, Wang R, Wu HL, et al. Serum amyloid A mediates the inhibitory effect of Ganoderma lucidum polysaccharides on tumor cell adhesion to endothelial cellsOncol Rep. Sep 2008;20(3):549-556.
  74. Chan WK, Cheung CC, Law HK, et al. Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory functionJ Hematol Oncol. 2008;1(1):9.
  75. Noguchi M, Kakuma T, Tomiyasu K, et al. Effect of an extract of Ganoderma lucidum in men with lower urinary tract symptoms: a double-blind, placebo-controlled randomized and dose-ranging study. Asian J Androl. 2008 Jul;10(4):651-8.
  76. Weng CJ, Yen GC. The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis. Clin Exp Metastasis. 2010 May;27(5):361-9.
  77. Kim KC, Jun HJ, Kim JS, Kim IG. Enhancement of radiation response with combined Ganoderma lucidum and Duchesnea chrysantha extracts in human leukemia HL-60 cells. Int J Mol Med. 2008 Apr;21(4):489-98.
  78. Gordan JD, Chay WY, Kelley RK, et al. “And what other medications are you taking?”. J Clin Oncol. 2011 Apr 10;29(11):e288-91.
  79. Yuen MF, Ip P, Ng WK, Lai CL. Hepatotoxicity due to a formulation of Ganoderma lucidum (lingzhi). J Hepatol. 2004 Oct;41(4):686-7.
  80. Wanmuang H, Leopairut J, Kositchaiwat C, Wananukul W, Bunyaratvej S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007 Jan;90(1):179-81.
  81. Wanachiwanawin D, Piankijagum A, Chaiprasert A, et al. Ganoderma lucidum: a cause of pseudoparasitosis. Southeast Asian J Trop Med Public Health. 2006 Nov;37(6):1099-102.
  82. Zhao S, Ye G, Fu G, Cheng JX, Yang BB, Peng C. Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin. Int J Oncol. 2011 May;38(5):1319-27.
  83. Pillai TG, John M, Sara Thomas G. Prevention of cisplatin induced nephrotoxicity by terpenes isolated from Ganoderma lucidum occurring in Southern Parts of India. Exp Toxicol Pathol. 2011 Jan;63(1-2):157-60.
  84. Chu TT, Benzie IF, Lam CW, et al. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br J Nutr. 2012 Apr;107(7):1017-27.
  85. Jin X, Ruiz Beguerie J, Sze DM, Chan GC . Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev. 2012 Jun 13;6:CD007731.
  86. Chang CJ, Chen YY, Lu CC, et al. Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin. Innate Immun. 2014 Apr;20(3):301-11.
  87. Sun LX, Lin ZB, Duan XS, et al. Enhanced MHC class I and costimulatory molecules on B16F10 cells by Ganoderma lucidum polysaccharides. J Drug Target.2012 Aug;20(7):582-92.
  88. Boh B, Berovic M, Zhang J, Zhi-Bin L. Ganoderma lucidum and its pharmaceutically active compounds. Biotechnol Annu Rev. 2007;13:265-301.
  89. Paterson RR. Ganoderma - a therapeutic fungal biofactory. Phytochemistry. 2006 Sep;67(18):1985-2001.
  90. Liang Y, He M, Fan X, et al. An abnormal elevation of serum CA72-4 by Ganoderma lucidum spore powder. Ann Clin Lab Sci. 2013 Summer;43(3):337-40.
  91. Joseph S, Sabulal B, George V, Antony KR, Janardhanan KK. Antitumor and anti-inflammatory activities of polysaccharides isolated from Ganoderma lucidum. Acta Pharm. 2011 Sep 1;61(3):335-42.
  92. Jin H, Jin F, Jin JX, et al. Protective effects of Ganoderma lucidum spore on cadmium hepatotoxicity in mice. Food Chem Toxicol. 2013 Feb;52:171-5.
  93. Klupp NL, Chang D, Hawke F, et al. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015;2:CD007259.
  94. Ko KK, Murthee KG, Koh TH, et al. Reishi (lingzhi) ingestion mistaken for persistent Clonorchis infection. Pathology. Oct 2014;46(6):576-578.
  95. Sun LX, Li WD, Lin ZB, et al. Protection against lung cancer patient plasma-induced lymphocyte suppression by Ganoderma lucidum polysaccharides. Cell Physiol Biochem. 2014;33(2):289-299.
  96. Oka S, Tanaka S, Yoshida S, et al. A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas. Hiroshima J Med Sci. Mar 2010;59(1):1-6.
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  101. Wu K, Na K, Chen D, et al. Effects of non-steroidal anti-inflammatory drug-activated gene-1 on Ganoderma lucidum polysaccharides-induced apoptosis of human prostate cancer PC-3 cells. Int J Oncol. Dec 2018;53(6):2356-2368.
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Most Supplements Stop at Standard. We Don’t.

Every detail, from sourcing to formulationn is considered to ensure that when you choose Polyextract, you’re choosing an extract that goes far beyond industry standards.

No shortcuts. No compromises. Just premium quality, start to finish.

  • Vegan

  • Gluten-Free

  • Certified Organic

  • No Animal Testing

  • No-Binders

  • Allergen-Free

  • 100% EU Ingredients

  • GMO-Free

Making each dose work harder for you.

  • Selection

    The concentration of active compounds in mushrooms depends heavily on how the fungi is grown.

    That’s why we’ve established a direct partnership with our organic mushroom farmer in Belgium allowing us to oversee everything from the strain selection and substrate composition to the harvest timing and delivery conditions.

  • Innovation

    We spent 2 years developing our extraction protocol, conducting more than 50 formulation trials and analyzing each batch in depth.

    Using high-end analytical tools like HPLC, we optimized our method to extract the broadest spectrum of compounds. This work laid the foundation for an ongoing scientific thesis, positioning Polyextract at the forefront of research in the field.

  • Extraction

    To capture all active compounds, we apply up to 5 extraction techniques per mushroom, tailored by species and compound profile.

    Each method is optimized individually, then recombined to ensure molecular stability and bioavailability. This multi-step approach makes our extraction process unique in the industry, built not on assumption, but on data.

  • Assimilation

    Our extract allows faster, more efficient absorption. This is thanks to our liquid formulation, which bypasses the digestive breakdown required by capsules or powders.

    Think of it as a pre-digested supplement. When active compounds are pre-dissolved, your body works less and absorbs more. Some compounds have shown up to 185× better absorption in liquid form.

Questions ? We're here to help you.

How do I take this TriExtract ?

Take x1 full dropper pipette (1 mL) per day.

Mix it into a glass of water or any other cold liquid.You can also take it directly under the tongue.

________________

For best results:

  • Take consistently. Our TriExtract works best when used daily over time.
  • Avoid mixing with hot liquids, as heat may affect the stability of some sensitive compounds.
  • Take at the same time each day, ideally within one hour of your usual wake-up and wind-down times to stay aligned with your circadian rhythm.
  • During high-demand periods (mental or physical), you may temporarily increase to 30–40 drops per day (1.5 to 2 full pipettes), split between morning and evening.
  • Start with 5 drops in the morning and 5 in the evening. Then, Increase daily by +2 drops total (add 1 drop to each dose) until you reach 20 drops per day by day 6 (10 in the morning, 10 in the evening).
  • Always Shake well before use.

________________

x1 dropper pipette = 1 mL = 0.0338 oz. ≈ x20 dropps

Do not exceed 50 drops per day.

Do not use if under 18 years old, or if you are a pregnant/breastfeeding women.

What’s Inside the TriExtract ?

1/3 Wild-Harvested Organic Chaga - Inonotus obliquus

1/3 Organic Reishi Ganoderma lucidum

1/3 Organic Lion's Mane Hericium erinaceus

  • 100% Organic - Certified by Ecocert (EU Agriculture)
  • Fruiting Body (100%) - no fillers
  • Origin: BE (Reishi, Lion’s Mane), EE / RU (Chaga)

Other Ingredients: Purified Water, Food Grade Organic Ethanol (20-24%)*

And nothing else !

*Note: Ethanol is used as a solvent to extract and stabilize bioactive compounds and enhance product bioavailability.

Why should I choose Polyextract Supplement ?

At Polyextract, we combine traditional knowledge with modern extraction science. Our formulas are:

Made from 100% fruiting bodies, organically grown or wild-harvested

Certified organic by Ecocert (EU Agriculture)

Free from fillers, artificial preservatives, or synthetic additives

Triple-extracted Liquid Form for maximum compound diversity and bioavailability

Our triple-extraction process uses hot water, ethanol, and ultrasonic methods to capture and preserve a wide array of beneficial molecules like beta-glucans, hericenones, ganoderic acids, melanin, and triterpenes. This method ensures efficient absorption and delivery to your system.

Each batch is carefully crafted in France and tested to ensure purity and consistency. We focus on full-spectrum mushroom extracts, providing you with the complete range of naturally occurring compounds, delivered in a liquid form for better bioavailability and easier daily use.

Compared to raw mushrooms powders or single-method extracts, Polyextract’s TriExtract offers a more complete and concentrated formula, designed for those who seek practical, consistent, and science-informed support for body and mind.

When will I feel something?

Everyone responds differently—but many users start to notice subtle benefits within the first two weeks of consistent use.

Typical Timeline

  • Days to 2 Weeks: Gentle effects like improved sleep quality, relaxation, and a more balanced mood may begin to appear.
  • 2 to 4 Weeks: Users often report clearer thinking, better focus, steady energy, and initial immune support.
  • 1 to 3 Months: With daily use, deeper effects may emerge, such as improved resilience, enhanced cognitive performance, and a more balanced immune response.

TriExtract combines Chaga, Reishi, and Lion’s Mane in a liquid, bioavailable form designed for gradual, long-term support, not a quick fix. That means you may not “feel” a dramatic shift overnight. Instead, the active compounds, such as beta-glucans, triterpenes, and hericenones, work quietly in the background, supporting your body’s natural balance day after day.

What does Chaga, Reishi, Lion's Mane Mushroom extract do?

Lion’s Mane (Hericium erinaceus), Chaga (Inonotus obliquus), and Reishi (Ganoderma lucidum), each offer a distinct profile of naturally occurring compounds studied for their potential to support:


Cognitive function and mental clarity (Lion’s Mane – contains hericenones and erinacines, studied for their influence on nerve growth factor in preclinical models)

Immune system modulation and antioxidant defense (Chaga – rich in polyphenols, melanin, and triterpenes, studied for their antioxidant activity and cellular support)

Stress adaptation and balance (Reishi – source of beta-glucans and ganoderic acids, traditionally associated with immune balance and adaptogenic properties)

You can explore the research associated with these compounds in our Scientific Reference Library above.

Can I take TriEextract with other supplements or medications?

Yes, many people include TriExtract in their broader supplement routine, and there are no known contraindications.

If you’re combining it with other products, we recommend spacing doses throughout the day and observing how your body responds.

____________

As with any supplement, it’s best to consult your physician before starting, especially if you’re on prescription medication or managing a health condition.

Our extracts are highly concentrated and more potent than typical food forms. If you're on medication (especially for immunity, blood thinning, or blood sugar), have epilepsy, or a medical condition, we recommend consulting your healthcare provider.

Some users report feeling increased mental clarity after taking the extract, especially when taken in the evening, which may delay sleep for those sensitive to stimulation. If this applies to you, we recommend shifting the evening dose to early afternoon to avoid potential alertness later in the day.

Who It’s For ?

Adults 40+ seeking daily support for energy, clarity, and long-term balance.

Individuals looking to complement their lifestyle with functional compounds studied for their roles in immune and cognitive support.

Those interested in natural, performance-focused supplementation rooted in both tradition and modern scientific research.

Customer Reviews

Based on 13 reviews
85%
(11)
15%
(2)
0%
(0)
0%
(0)
0%
(0)
S
Sylvie O.
well received

We started the cure but seems to early to give you te effects expecting good.

Reviews in Other Languages

A
Anonymous
Amélioration

Mieux pour l'arthrose

I
Isabelle
Etonnant !

Je prends cet extrait depuis 1mois et demi. Je me sens plus dynamique et motivée.
Je compte poursuivre car je pars de très loin… !
Le petit bémol c’est son prix…

S
Sandra
Bon produit, et surtout avec résultats

J ai commencé le réishi car j etais fatigué. Au bout de 15 jours, mon entourage et moi même avons constaté une nette amélioration !
Je continue !